Introduction to the Session – Juan Patricio Nogueira (Argentina)

Genetics of hypercholesterolemia with the focus on monogenic forms – Robert Hegele (Canda)

Natural history of homozygous FH and its epidemiology in LATAM – Rodrigo Alonso (Chile)

Defining the severe FH phenotype and its implications – Raul Santos (Brazil)

Discussion Forum 3 – Panelist Pablo Corral (Argentina)

Co-chair summary of the lectures key messages – Juan Patricio Nogueira (Argentina)

Introduction to the session Maria Cristina Izar (Brazil)

Severe pediatric hypercholesterolemia – Samuel Gidding (USA)

PCSK9 inhibitors in severe FH – Maria Cristina Izar (Brazil)

Lomitapide efficacy and safety in homozygous FH – Dirk Blom (South Africa)

Novel therapies for severe FH – Paola Varleta (Chile)

Discussion Forum 4 – Panelist Roopa Mehta (Mexico)

Co-chair summary of the lectures key messages – Maria Cristina Izar (Brazil)